[Association between the feeding behavior factors and the expression of DRD2 gene: a study of mexican monozygotic twins].

INTRODUCTION The feeding behavior in humans is complex, with psychological, social, and cultural factors. This pathology consists of the desire to eat (reinforcement/reward) and the control of the act of eating (inhibitory control). It is well known that blocking post-synaptic D2 receptors in the nucleus accumbens induces a decrease of craving behavior. Due to this, to test hypothesis we measured the expression of the DRD2 gene and the expression of the type of feeding factor in a group of Mexican twins. METHODS In the study were included 18 pairs of twins (n = 36), reared together (at least up to 18 years old); native to Mexico City; to whom we applied the three factors of food instrument. RESULTS We observed a significant correlation between the "uncontrolled" factor and expression of the DRD2 gene (p < 0.03). CONCLUSION Therefore, we propose that the expression of the DRD2 gene in subjects is a linkage to the type of feeding factor.